Idylla ctNRAS-BRAF-EGFR S492R Mutation Assay

18 mutations in NRAS exons 2,3 and 4, 5 mutations in BRAF codon 600 and 2 EGFR mutations in codon 492

~110 minutes assay turnaround time

< 1 minute hands-on time

Only 1 ml of plasma required

Highly sensitive & standardized

Suitable for any lab

Idylla ctNRAS-BRAF-EGFR S492R Mutation Assay (RUO)

A0091/6

The fully automated Idylla^TM ctNRAS-BRAF-EGFR S492R Mutation Assay is minimally invasive, fast and easy to perform. ctNRAS-BRAF-EGFR S492R covers 18 mutations in NRAS exons 2,3 and 4, 5 mutations in BRAF codon 600 as well as 2 EGFR mutations in codon 492 and showed an high concordance of 100% for NRAS as well as 99.5% for BRAF compared to NGS using plasma samples from 198 mCRC patients enrolled in the prospective multicenter RASANC study.1

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For research use only. Not for use in diagnostic procedures.

1Jacobs et al. Journal of Clinical Oncology 2017; 35,15_suppl e15127

Specimen requirements

One of the biggest challenges in oncology biomarker testing is the ability to obtain samples of sufficient size and quality. With the Idylla^TM System only a minimal amount of sample is needed

1 ml plasma collected using either EDTA or Streck tubes

NOTE:

K₂EDTA tubes: process within 4 hours
Streck Cell-free BCTs: process within 3 days

Idylla Research Assays

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