Idylla BRAF Mutation Test

7 BRAF mutations in codon 600

~90 minutes assay turnaround time

< 2 minutes hands-on time

Only 1 slice of FFPE tissue required

Highly sensitive & standardized

Suitable for any lab

Idylla BRAF Mutation Test (CE-IVD)

A0010/6

The fully automated Idylla^TM BRAF Mutation Test covers BRAF V600E, E2, D, K, R and M mutation with a sensitivity of 1% of mutant in wild type background in FFPE samples with an excellent concordance to reference methods of >95%.

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For more information on the MGB Probe license, click here.

Specimen requirements

One of the biggest challenges in oncology biomarker testing is the ability to obtain samples of sufficient size and quality. With the Idylla^TM System only a minimal amount of sample is needed

1x 5 μm FFPE tissue section -> 50-600 mm²
1x 10 μm FFPE tissue section -> 25-300 mm²
Neoplastic cells ≥50% - if less, macrodissection is required

Rapid BRAF mutation tests in patients with advanced melanoma: comparison of immunohistochemistry, Droplet Digital PCR, and the Idylla Mutation Platform.

Bisschop et al. - Melanoma Research - 2018

The Idylla^TM BRAF Mutation Test was compared to ddPCR, IHC, and Sanger Sequencing for testing BRAF V600 mutation. BRAF results were 100% concordant between Idylla, ddPCR, and Sanger Sequencing.

Multicenter evaluation of a novel automated rapid detection system of BRAF status in formalin-fixed, paraffin-embedded tissues

Schiefer et al. - J Mol Diagn. - May 2016

Idylla Oncology Assays

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