Oncology Research Assays

*UNDER DEVELOPMENT

For the detection of the hypermutated phenotype associated with mutations in POLE and POLD1.

Fully-automated detection of 21 KRAS mutations in exons 2,3 and 4 directly from a single slice of FFPE tissue

Fully-automated detection of 7 BRAF mutations in codon 600 directly from a single slice of FFPE tissue

Fully-automated detection of 18 mutations in NRAS exons 2,3 and, 5 mutations in BRAF codon 600 as well as  2 EGFR mutations in codon 492 directly from a single slice of FFPE tissue

Fully-automated detection of 51 EGFR mutations in exons 18,19,20 and 21 directly from a single slice of FFPE tissue

* UNDER DEVELOPMENT
First-in-class cartridge-based assay for indeterminate thyroid nodules. For Research Use Only, assay currently under development.

The APIS ESR1 Mutations Kit is an advanced qPCR assay for the sensitive and precise detection of mutations within the oestrogen receptor gene. The APIS ESR1 Mutations Kit is a qualitative test, detecting eleven ESR1 mutations across three exons: exon 5 (E380Q), exon 7 (S463P) and exon 8 (P535H, L536R, L536Q, L536H, L536P, Y537C, Y537S, Y537N and D538G).

An assay for the molecular characterization of hormone receptor positive (HR+) HER2 negative (HER2-) metastatic breast cancer. For Research Use Only.

The fully automated Idylla™ IDH1-2 Mutation Assay Kit performs detection of 5 mutations in the isocitrate dehydrogenase 1 gene (IDH1) and 10 mutations in the isocitrate dehydrogenase 2 gene (IDH2).

The fully automated Idylla GeneFusion Assay detects ALK, ROS1, RET, NTRK1/2/3 rearrangements & MET exon 14 skipping in a single cartridge.

Idylla ctEGFR covers 49 EGFR mutations in exons 18, 19, 20 & 21 and showed high concordance compared to NGS.

Fully-automated detection of 18 mutations in NRAS exons 2,3 and, 5 mutations in BRAF codon 600 as well as  2 EGFR mutations in codon 492 directly from 1ml plasma.